YZ167 | HDAC6 PROTAC | Probechem Biochemicals

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Chemical Structure : YZ167

Catalog No.: PC-22938Not For Human Use, Lab Use Only.

YZ1678 is a potent, selective HDAC6 PROTAC degrader with DC50 of 1.94 nM in MM.1S cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

YZ1678 is a potent, selective HDAC6 PROTAC degrader with DC50 of 1.94 nM in MM.1S cells.

M.Wt	615.69
Formula	C33H37N5O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-(2-(4-((5-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pent-4-yn-1-yl)oxy)benzylidene) hydrazineyl)-N-hydroxy-8-oxooctanamide

1. Ka Yang, et al. Cell Chem Biol. 2020 Jul 16;27(7):866-876.e8.