Z1780628919

Chemical Structure : Z1780628919

Catalog No.: PC-23364Not For Human Use, Lab Use Only.

Z1780628919 is a small molecule ligand and antagonist of GRP39, inhibits TC-G-1008-induced inflammatory effects in HUVECs, significantly attenuates Ang II-induced hypertension in mice.

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Biological Activity

Z1780628919 is a small molecule ligand and antagonist of GRP39, inhibits TC-G-1008-induced inflammatory effects in HUVECs, significantly attenuates Ang II-induced hypertension in mice.

Physicochemical Properties

M.Wt	364.40
Formula	C18H22F2N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(6-(difluoromethoxy)-1,2,3,4-tetrahydronaphthalen-1-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-1-carboxamide

References

1. Hua D, et al. Commun Biol. 2024 Nov 5;7(1):1441.

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Z1780628919

Biological Activity

Physicochemical Properties

References

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