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You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-Potassium Channel-Z299576254
Z299576254

Chemical Structure : Z299576254

CAS No.: 1210503-30-2

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Z299576254

Catalog No.: PC-28404Not For Human Use, Lab Use Only.

Z299576254 is a safe and potent voltage-gated potassium channel Kv1.3 inhibitor, suppresses macrophage inflammatory responses by modulating the PI3K/AKT signaling pathway.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Z299576254 is a safe and potent voltage-gated potassium channel Kv1.3 inhibitor, suppresses macrophage inflammatory responses by modulating the PI3K/AKT signaling pathway.
Z299576254 suppresses the inflammatory response in RAW264.7 cells
Z299576254 ameliorates alcoholic liver injury by inhibiting Kv1.3.
Z299576254 exerts anti-inflammatory effects via the PI3K/AKT signaling pathway.

Physicochemical Properties

M.Wt 495.60
Formula C25H29N5O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((2-(cyclohexyl(methyl)amino)-2-oxoethyl)thio)-N-(2-oxo-2-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)amino)ethyl)benzamide

References

1. Wen-Jun Zhen, et al. Eur J Med Chem. 2026 Sep 19:320:119310.

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