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Chemical Structure : Z62954982
CAS No.: 1090893-12-1
Catalog No.: PC-63241Not For Human Use, Lab Use Only.
Z62954982 is a potent, specific Rac1 inhibitor, reduces the intracellular levels of Rac1-GTP in a concentration-dependent manner with IC50 of 12 uM, 4 times more effective than NSC23766 (IC50=50 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $138 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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Z62954982 is a potent, specific Rac1 inhibitor, reduces the intracellular levels of Rac1-GTP in a concentration-dependent manner with IC50 of 12 uM, 4 times more effective than NSC23766 (IC50=50 uM).
Z62954982 causes a concentration-dependent decrease in transendothelial electrical resistance (TER) in both HDMEC and HUVEC.
| M.Wt | 415.464 | |
| Formula | C20H21N3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-((3,5-Dimethylisoxazol-4-yl)methoxy)-N-(4-methyl-3-sulfamoyl-phenyl)benzamide |
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1. Zhang XE, et al. PLoS One. 2016 May 17;11(5):e0155490.
2. Lobastova L, et al. Cell Oncol (Dordr). 2017 Feb;40(1):63-76.
3. Yamaguchi N, et al. Sci Rep. 2015 Jan 7;5:7656.
4. Ferri N, et al. J Med Chem. 2009 Jul 23;52(14):4087-90.
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