ZCAN155 | GluA2 modualtor | Probechem Biochemicals

Chemical Structure : ZCAN155

ZCAN155 (ZCAN 155)

Catalog No.: PC-21624Not For Human Use, Lab Use Only.

ZCAN155 is a small molecule that prevents AMPA-mediated excitotoxicity (IC50=35 nM) by targeting an allosteric binding site of AMPA glutamate receptor 2 (GluA2), restores neurological function and myelination.

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Biological Activity

ZCAN155 is a small molecule that prevents AMPA-mediated excitotoxicity (IC50=35 nM) by targeting an allosteric binding site of AMPA glutamate receptor 2 (GluA2), restores neurological function and myelination.

Physicochemical Properties

M.Wt	366.40
Formula	C19H19FN6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-(4-fluorobenzyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl)-N,N-dimethylpyrimidine-4-carboxamide

References

1. Zhai D, et al. Sci Adv. 2023 Dec 8;9(49):eadj6187.

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ZCAN155 (ZCAN 155)

Biological Activity

Physicochemical Properties

References

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