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ZCAN155

Chemical Structure : ZCAN155

CAS No.: 2485743-34-6

ZCAN155 (ZCAN 155)

Catalog No.: PC-21624Not For Human Use, Lab Use Only.

ZCAN155 is a small molecule that prevents AMPA-mediated excitotoxicity (IC50=35 nM) by targeting an allosteric binding site of AMPA glutamate receptor 2 (GluA2), restores neurological function and myelination.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ZCAN155 is a small molecule that prevents AMPA-mediated excitotoxicity (IC50=35 nM) by targeting an allosteric binding site of AMPA glutamate receptor 2 (GluA2), restores neurological function and myelination.

Physicochemical Properties

M.Wt 366.40
Formula C19H19FN6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(2-(4-fluorobenzyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl)-N,N-dimethylpyrimidine-4-carboxamide

References

1. Zhai D, et al. Sci Adv. 2023 Dec 8;9(49):eadj6187.

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