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ZCL278

Chemical Structure : ZCL278

CAS No.: 587841-73-4

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ZCL278 (ZCL 278, ZCL-278)

Catalog No.: PC-43811Not For Human Use, Lab Use Only.

ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM).
ZCL278 specifically targets Cdc42-intersectin interaction and inhibits Cdc42-mediated cellular processes, including Golgi organization and cell motility.

Physicochemical Properties

M.Wt 584.8937
Formula C21H19BrClN5O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Acetamide, 2-(4-bromo-2-chlorophenoxy)-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]thioxomethyl]-

References

1. Friesland A, et al. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1261-6.

2. Liu X, et al. Cell Physiol Biochem. 2015;36(4):1613-27.

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