Chemical Structure : ZCL278
CAS No.: 587841-73-4
Catalog No.: PC-43811Not For Human Use, Lab Use Only.
ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM).
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ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM).
ZCL278 specifically targets Cdc42-intersectin interaction and inhibits Cdc42-mediated cellular processes, including Golgi organization and cell motility.
M.Wt | 584.8937 | |
Formula | C21H19BrClN5O4S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Acetamide, 2-(4-bromo-2-chlorophenoxy)-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]thioxomethyl]- |
1. Friesland A, et al. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1261-6.
2. Liu X, et al. Cell Physiol Biochem. 2015;36(4):1613-27.
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