ZINC-3573 racemate |CAS:1378183-16-4 Probechem Biochemicals

Chemical Structure : ZINC-3573 racemate

ZINC-3573 racemate (ZINC3573 racemate)

Catalog No.: PC-62228Not For Human Use, Lab Use Only.

ZINC-3573 racemate is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=3 uM), showing little activity against 315 other GPCRs and 97 representative kinases.

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Biological Activity

ZINC-3573 racemate is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=3 uM), showing little activity against 315 other GPCRs and 97 representative kinases.
ZINC-3573 activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.

Physicochemical Properties

M.Wt	307.401
Formula	C18H21N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Dimethyl-[1-(5-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)-pyrrolidin-3-yl]-amine

References

1. Lansu K, et al. Nat Chem Biol. 2017 May;13(5):529-536.

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ZINC-3573 racemate (ZINC3573 racemate)

Biological Activity

Physicochemical Properties

References

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