ZJCK-6-72

Chemical Structure : ZJCK-6-72

Catalog No.: PC-26800Not For Human Use, Lab Use Only.

ZJCK-6-72 is a highly potent, orally bioavailable, blood-brain barrier (BBB) permeable DYRK1A inhibitor with IC50 of 8.64 nM.

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Biological Activity

ZJCK-6-72 is a highly potent, orally bioavailable, blood-brain barrier (BBB) permeable DYRK1A inhibitor with IC50 of 8.64 nM.

M.Wt	421.50
Formula	C26H23N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-(6-(6-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)quinazolin-4-yl)-2-phenylmorpholine

1. Zhenshu Li, et al. Front Pharmacol. 2026 May 1:17:1792258.