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Chemical Structure : ZLN-005
CAS No.: 49671-76-3
Catalog No.: PC-45338Not For Human Use, Lab Use Only.
ZLN-005 is a small molecule peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) transcriptional activator, increases expression of the PGC-1α gene and downstream genes by activation of AMP-activated protein kinase (AMPK).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg (Free Sample) | $28 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $298 | In stock | |
| 250 mg | Get quote |
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ZLN-005 is a small molecule peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) transcriptional activator, increases expression of the PGC-1α gene and downstream genes by activation of AMP-activated protein kinase (AMPK).
ZLN-005 improves glucose uptake and fatty acid oxidation without obvious cytotoxicity in L6 myotubes.
ZLN-005 produces antihyperglycemia and antihyperlipidemia effects and increases insulin sensitivity in db/db mice.
| M.Wt | 250.3382 | |
| Formula | C17H18N2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 47 mg/mL |
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| Chemical Name/SMILES |
1H-Benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]- |
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1. Zhang LN, et al. Diabetes. 2013 Apr;62(4):1297-307.
2. Kadlec AO, et al. Hypertension. 2017 Jul;70(1):166-173.
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