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Chemical Structure : ZM145
Catalog No.: PC-21995Not For Human Use, Lab Use Only.
ZM145 (pNPS145) is a small molecule inhibitor of phospho-BRD4 (pBRD4) with IC50 of 2.5 uM, binds to phospho-NPS (pNPS) and disrupts HPV E2-BRD4 interaction, effectively inhibits HPV ecDNA replication.
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ZM145 (pNPS145) is a small molecule inhibitor of phospho-BRD4 (pBRD4) with IC50 of 2.5 uM, binds to phospho-NPS (pNPS) and disrupts HPV E2-BRD4 interaction, effectively inhibits HPV ecDNA replication.
| M.Wt | 361.42 | |
| Formula | C20H15N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wu SY, et al. Mol Cell. 2024 Jan 18;84(2):202-220.e15.
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