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ZM600

Chemical Structure : ZM600

CAS No.: 3030125-00-6

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ZM600 (ZM 600, ZM-600)

Catalog No.: PC-22689Not For Human Use, Lab Use Only.

ZM600 is a novel antihepatic fibrosis compound that shows significant inhibitory effect on the activation of hepatic stellate cells (HSCs), specifically inhibits the activation of NF-κB, PI-3K/AKT, and TGF-β/Smads signaling pathways.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ZM600 is a novel antihepatic fibrosis compound that shows significant inhibitory effect on the activation of hepatic stellate cells (HSCs), specifically inhibits the activation of NF-κB, PI-3K/AKT, and TGF-β/Smads signaling pathways.

Physicochemical Properties

M.Wt 506.66
Formula C31H39FN2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

methyl 4-((1R,3aR,3a1S,10aR)-2-(2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoyl)decahydro-1H,4H-pyrido[3,2,1-ij][1,6]naphthyridin-1-yl)butanoate

References

1. Guoqing Li, et al. J Med Chem. 2024 Jul 11;67(13):11389-11400.

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