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Chemical Structure : ZSET1446
CAS No.: 887603-94-3
Catalog No.: PC-42788Not For Human Use, Lab Use Only.
ZSET1446 (ST-101) is a small molecule cognitive enhancer that potentiates acetylcholine-mediated facilitation of inhibitory synaptic transmission in the hippocampal neurons.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $248 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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ZSET1446 (ST-101) is a small molecule cognitive enhancer that potentiates acetylcholine-mediated facilitation of inhibitory synaptic transmission in the hippocampal neurons.
ZSET1446 (ST-101) increases the extracellular ACh in the cortex and hippocampus and enhances nicotine-stimulated ACh release in the hippocampus in normal rats, without affecting nAChRs.
| M.Wt | 236.2686 | |
| Formula | C15H12N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 34 mg/mL |
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| Chemical Name/SMILES |
Spiro[imidazo[1,2-a]pyridine-3(2H),2'-[2H]inden]-2-one, 1',3'-dihydro- |
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1. Yamaguchi Y, et al. J Pharmacol Exp Ther. 2006 Jun;317(3):1079-87.
2. Ito Y, et al. J Pharmacol Exp Ther. 2007 Feb;320(2):819-27.
3. Han F, et al. J Pharmacol Exp Ther. 2008 Jul;326(1):127-34.
4. Shioda N, et al. J Pharmacol Exp Ther. 2010 Apr;333(1):43-50.
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