ZXH-1-161

You are here:Home-ADCs and PROTACs-PROTAC-ZXH-1-161

Chemical Structure : ZXH-1-161

Catalog No.: PC-47018Not For Human Use, Lab Use Only.

ZXH-1-161 is a potent, selective small-molecule GSPT1 degrader, inhibits ceell viability in MM1.S with IC50 of 39 nM.

Packing	Price	Stock	Quantity
100 mg		Get quote
250 mg		Get quote
500 mg		Get quote
1 g		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ZXH-1-161 is a potent, selective small-molecule GSPT1 degrader, inhibits ceell viability in MM1.S with IC50 of 39 nM.

ZXH-1-161 is a superior tool to CC-885 for exploring the therapeutic potential of GSPT1 degradation and may provide additional opportunities for therapeutically targeting GSPT1.

Physicochemical Properties

M.Wt	468.52
Formula	C26H24N6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-((2-((2,3-dihydro-1H-inden-5-yl)amino)pyrimidin-4-yl)amino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

References

1. Chelsea E Powell, et al. ACS Chem Biol. 2020 Oct 16;15(10):2722-2730.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

Select Your Country or Region

ZXH-1-161

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.