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Chemical Structure : ZYZ-488
CAS No.: 1470302-79-4
Catalog No.: PC-62212Not For Human Use, Lab Use Only.
ZYZ-488 is a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1), inhibits the activation of binding protein procaspase-9 and procaspase-3.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $298 | In stock | |
| 10 mg | $478 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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ZYZ-488 is a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1), inhibits the activation of binding protein procaspase-9 and procaspase-3.
ZYZ-488 exhibits cardioprotective effects on hypoxia-induced H9c2 rat ventricular cells.
ZYZ-488 decreases apoptosis in hypoxic H9c2 cells, shows potential for treating cardiac ischemia.
| M.Wt | 487.462 | |
| Formula | C20H29N3O11 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2S,3S,4S,5R,6S)-6-(4-((4-guanidinobutoxy)carbonyl)-2,6-dimethoxyphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid |
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1. Wang Y, et al. Sci Rep. 2016 Jul 22;6:29820.
2. Wang Y, et al. Oxid Med Cell Longev. 2017;2017:9747296.
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