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Chemical Structure : Zanapezil
Catalog No.: PC-63361Not For Human Use, Lab Use Only.
Zanapezil (TAK-147) is a potent, selective acetylcholinesterase (AChE) inhibitor with IC50 of 97.7 nM.
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Zanapezil (TAK-147) is a potent, selective acetylcholinesterase (AChE) inhibitor with IC50 of 97.7 nM。
Zanapezil (TAK-147) ameliorates the passive avoidance deficit induced by diazepam in animal models at 1-3 mg/kg。
Zanapezil (TAK-147) ameliorates the impairment of DMTP performance induced by scopolamine without affecting the general behavior of the rats.
| M.Wt | 492.616 | |
| Formula | C29H36N2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hatip-Al-Khatib I, et al. Br J Pharmacol. 2005 Aug;145(8):1035-44.
2. Hirai K, et al. J Pharmacol Exp Ther. 1997 Mar;280(3):1261-9.
3. Miyamoto M, et al. J Pharmacol Exp Ther. 1996 Jun;277(3):1292-304.
4. Ishihara Y, et al. J Med Chem. 1994 Jul 22;37(15):2292-9.
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