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Zelasudil

Chemical Structure : Zelasudil

CAS No.: 2365193-22-0

Zelasudil (RXC007, RXC-007)

Catalog No.: PC-27873Not For Human Use, Lab Use Only.

Zelasudil (RXC007) is a potent, orally active, highly selective small molecule Rho-associated coiled-coil containing protein kinase 2 (ROCK2) inhibitor, shows anti-fibrotic efficacy.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Zelasudil (RXC007) is a potent, orally active, highly selective small molecule Rho-associated coiled-coil containing protein kinase 2 (ROCK2) inhibitor, shows anti-fibrotic efficacy.

Physicochemical Properties

M.Wt 437.45
Formula C22H21F2N7O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(5-((4-Cyclopropyl-1H-indazol-5-yl)amino)-1-methyl-1H-1,2,4-triazol-3-yl)-N-(2,2-difluoroethyl)benzamide

References

1. Marina Pajic, et al. Cancer Res (2024) 84 (6_Supplement): 720.

2. Patent WO2022169946. 2022-08-11.

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