Zenagamtide | GLP-1/Amylin receptor agonist

Chemical Structure : Zenagamtide

CAS No.: 3005889-81-3

Zenagamtide (Amycretin, NN 9487)

Catalog No.: PC-27447Not For Human Use, Lab Use Only.

Zenagamtide (Amycretin, NN 9487) is a unimolecular peptide, orally active, blood-brain barrier permeable triple agonist of GLP-1, amylin, and calcitonin receptors, significantly suppresses appetite and reduces energy intake, improves body weight, waist circumference, glycated hemoglobin and lipid profile, and also alleviates the histological features of metabolic dysfunction-associated steatotic liver disease (MASLD) and enhances insulin sensitivity.

Packing	Price	Stock
2 mg	$248	In stock
5 mg	$398	In stock
10 mg	$588	In stock
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Biological Activity

Physicochemical Properties

M.Wt	7846.60
Formula	C343H550N94O116
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Arg-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-{Lys(AEEA-AEEA-γGlu-C18 diacid)}-Gly-Gly-Gly-Gly-Glu-Ala-Ser-Glu-Leu-Ser-Thr-Ala-Ala-Leu-Gly-Arg-Leu-Ser-Ala-Glu-Leu-His-Glu-Leu-Ala-Thr-Leu-Pro-Arg-Thr-Glu-Thr-Gly-Ser-Gly-Ser-Pro-NH2

References

1. Mora P, et al. Lancet. 2026 Jul 30:S0140-6736(26)01247-X.

2. Oldenburg LIK, et al. Diabetes Obes Metab. 2026 Jul 13.

Zenagamtide (Amycretin, NN 9487)

Biological Activity

Physicochemical Properties

References

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