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Chemical Structure : Zidebactam
Catalog No.: PC-23241Not For Human Use, Lab Use Only.
Zidebactam (WCK-5107) is a β-Lactam Enhancer, inhibitor of class A, class C and some class D β-lactamases with MIC of <2 ug/ mL for most Escherichia coli , Klebsiella , Citrobacter and Enterobacter spp., also binds to penicillin-binding protein2 (PBP2).
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Zidebactam (WCK-5107) is a β-Lactam Enhancer, inhibitor of class A, class C and some class D β-lactamases with MIC of <2 ug/ mL for most Escherichia coli , Klebsiella , Citrobacter and Enterobacter spp., also binds to penicillin-binding protein2 (PBP2).
Zidebactam (WCK-5107) showed specific PBP2 inhibition and did not inhibit VIM-2.
Zidebactam (WCK-5107) exhibits direct antibacterial activity and a β-lactamase-independent 'enhancer' effect, potentiating β-lactams targeting PBP3.
| M.Wt | 391.40 | |
| Formula | C13H21N5O7S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Moya B, et al. Antimicrob Agents Chemother. 2017 May 24;61(6):e02529-16.
2. Livermore DM, et al. J Antimicrob Chemother. 2017 May 1;72(5):1373-1385.
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