Zinterol (MJ 9184) is a potent and selective β2 adrenoceptor agonist with pKb of 8.3, displays >2 logs selectivity over β1 (pKb<5.7).
Zinterol (MJ 9184) reduces response rate and increases reinforcement rate of rats under a differential-reinforcement-of-low-rate schedule in a dose-dependent manner.
Zinterol (MJ 9184) significant decreases in response rate and increases in reinforcement rate were observed at doses of 0.1-1 mg/kg.
