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Zinterol

Chemical Structure : Zinterol

CAS No.: 37000-20-7

Zinterol (MJ 9184)

Catalog No.: PC-62002Not For Human Use, Lab Use Only.

Zinterol (MJ 9184) is a potent and selective β2 adrenoceptor agonist with pKb of 8.3, displays >2 logs selectivity over β1 (pKb<5.7).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Zinterol (MJ 9184) is a potent and selective β2 adrenoceptor agonist with pKb of 8.3, displays >2 logs selectivity over β1 (pKb<5.7).
Zinterol (MJ 9184) reduces response rate and increases reinforcement rate of rats under a differential-reinforcement-of-low-rate schedule in a dose-dependent manner.
Zinterol (MJ 9184) significant decreases in response rate and increases in reinforcement rate were observed at doses of 0.1-1 mg/kg.

Physicochemical Properties

M.Wt 378.487
Formula C19H26N2O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[5-[2-[(1,1-Dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulphonamide

References

1. Skeberdis VA, et al. J Pharmacol Exp Ther. 1997 Nov;283(2):452-61.

2. Hutchinson DS, et al. Naunyn Schmiedebergs Arch Pharmacol. 2006 May;373(2):158-68.

3. O'Donnell JM. Psychopharmacology (Berl). 1993;113(1):89-94.

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