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Chemical Structure : Ziprasidone hydrochloride
CAS No.: 122883-93-6
Catalog No.: PC-43964Not For Human Use, Lab Use Only.
A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $132 | In stock | |
| 250 mg | Get quote |
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A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors; exhibits potent antipsychotic activity in vivo.
Schizophrenia
Approved
| M.Wt | 449.3966 | |
| Formula | C21H22Cl2N4OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride (1:1) |
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1. Mattei C, et al. J Cent Nerv Syst Dis. 2011 Feb 15;3:1-16.
2. Seeger TF, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13.
3. Schotte A, et al. Psychopharmacology (Berl). 1996 Mar;124(1-2):57-73.
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