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Zofenoprilat

Chemical Structure : Zofenoprilat

CAS No.: 75176-37-3

Zofenoprilat

Catalog No.: PC-27008Not For Human Use, Lab Use Only.

Zofenoprilat is a potent, specific angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.7 nM, exerts cardioprotective and renoprotective effects by inhibiting angiotensin II expression and lowering blood pressure.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Zofenoprilat is a potent, specific angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.7 nM, exerts cardioprotective and renoprotective effects by inhibiting angiotensin II expression and lowering blood pressure.

Physicochemical Properties

M.Wt 325.44
Formula C15H19NO3S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,4S)-1-((S)-3-Mercapto-2-methylpropanoyl)-4-(phenylthio)pyrrolidine-2-carboxylic acid

References

1. Ranadive SA, et al. Pharm Res. 1992;9(11):1480-1486.

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