Zolbetuximab
(Anti-human Claudin 18.2 mAb, human IgG1-Kappa)
Catalog No.: PC-Ab1015Not For Human Use, Lab Use Only.
Zolbetuximab is a first-in-class chimeric IgG1 mAb that specifically binds to Claudin 18 splice variant 2 (CLDN18.2) on the cell surface and mediates cell death through antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Claudin-18 (CLDN18) is a highly specific TJ component of the stomach. It is expressed in foetal and in adult normal gastric mucosa.
Zolbetuximab is a first-in-class chimeric IgG1 mAb that specifically binds to Claudin 18 splice variant 2 (CLDN18.2) on the cell surface and mediates cell death through antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Claudin-18 (CLDN18) is a highly specific TJ component of the stomach. It is expressed in foetal and in adult normal gastric mucosa
Physicochemical Properties
M.Wt
Formula
Human IgG1-Kappa
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
PBS, pH 7.0
Contains no stabilizers or preservatives
