Chemical Structure : Zosuquidar
CAS No.:
167354-41-8
Zosuquidar
(LY335979)
Catalog No. : PC-23700Not For Human Use, Lab Use Only.
Zosuquidar (LY335979) is a potent P-glycoprotein (P-gp) inhibitor with Ki of 60 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2370001
Biological Activity
Zosuquidar (LY335979) is a potent P-glycoprotein (P-gp) inhibitor with Ki of 60 nM.
Physicochemical Properties
M.Wt
527.62
Formula
C32H31F2N3O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-1-(4-((1aR,6r,10bS)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c][7]annulen-6-yl)piperazin-1-yl)-3-(quinolin-5-yloxy)propan-2-ol
References
1. Slate DL, et al. Anticancer Res. 1995 May-Jun;15(3):811-4.
2. Dantzig AH, et al. Cancer Res. 1996 Sep 15;56(18):4171-9.
3. Dantzig AH, et al. J Pharmacol Exp Ther. 1999 Aug;290(2):854-62.
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