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Zosurabalpin

Chemical Structure : Zosurabalpin

CAS No.: 2379336-76-0

Zosurabalpin (RG6006, RG 6006)

Catalog No.: PC-21953Not For Human Use, Lab Use Only.

Zosurabalpin is a small-molecule, tethered macrocyclic peptide antibiotic targeting the lipopolysaccharide transporter, has MIC of 0.06 ug/mL A. baumannii ATCC 17978.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Zosurabalpin is a small-molecule, tethered macrocyclic peptide antibiotic targeting the lipopolysaccharide transporter, has MIC of 0.06 ug/mL A. baumannii ATCC 17978.

Physicochemical Properties

M.Wt 790.98
Formula C43H50N8O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((7S,10S,13S)-13-((1H-indol-3-yl)methyl)-10-(4-aminobutyl)-7-(3-aminopropyl)-12-methyl-8,11,14-trioxo-5,6,7,8,9,10,11,12,13,14,15,16-dodecahydrobenzo[b]pyrido[3,2-p][1]thia[5,8,11,14]tetraazacycloheptadecin-17-yl)benzoic acid

References

1. Claudia Zampaloni, et al. Nature. 2024 Jan;625(7995):566-571.

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