c-FMS-IN-8 |CAS:885704-21-2 Probechem Biochemicals

Chemical Structure : c-FMS-IN-8

Catalog No.: PC-43376Not For Human Use, Lab Use Only.

c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.

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Biological Activity

c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.

M.Wt	406.5239
Formula	C23H30N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: 10 mM
Chemical Name/SMILES	1H-Pyrrole-2-carboxamide, 4-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-

1. Illig CR, et al. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8.

2. Meegalla SK, et al. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3632-7.