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Chemical Structure : dBET6
CAS No.: 1950634-92-0
Catalog No.: PC-61699Not For Human Use, Lab Use Only.
dBET6 is a highly potent, cell-permeable, optimized chemical degrader of BET bromodomain BRD4 with IC50 of 14 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $428 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
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| M.Wt | 841.381 | |
| Formula | C42H45ClN8O7S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]-2,3,9-trimethyl-, (6S)- |
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1. Winter GE, et al. Mol Cell. 2017 Jul 6;67(1):5-18.e19.
2. Cancer Discov. 2017 Aug;7(8):794.
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