dBRD4-BD1 | BRD4 PROTAC | Probechem Biochemicals

Chemical Structure : dBRD4-BD1

CAS No.: 2839318-19-1

Catalog No.: PC-49367Not For Human Use, Lab Use Only.

dBRD4-BD1 is a potent, selective degrader of BRD4 with DC50 of 280 nM, Dmax 77%.

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Biological Activity

dBRD4-BD1 is a potent, selective degrader of BRD4 with DC50 of 280 nM, Dmax 77%.

M.Wt	967.016
Formula	C50H53F3N8O9
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-N-(2-(2-(2-(4-(5-(2-(5-isopropyl-2-methylphenoxy)pyrimidin-4-yl)-4-(4-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)piperidin-1-yl)ethoxy)ethoxy)ethyl)acetamide

1. Anand Divakaran, et al. ACS Medicinal Chemistry Letters. 2022.