Chemical Structure : dBRD9 dihydrochloride
CAS No.:
2341840-98-8
dBRD9 dihydrochloride
(BRD9 PROTAC)
Catalog No. : PC-38462Not For Human Use, Lab Use Only.
dBRD9 dihydrochloride is a potent and selective degrader (PROTAC) of BRD9 with IC50 of 56.6 nM in MOLM-13 cells.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-3846201
Biological Activity
dBRD9 dihydrochloride is a potent and selective degrader (PROTAC) of BRD9 with IC50 of 56.6 nM in MOLM-13 cells.
Physicochemical Properties
M.Wt
856.755
Formula
C40H47Cl2N7O10
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-[[[4-(1,2-Dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2-6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]acetamide dihydrochloride
References
1. Remillard D, et al. Angew Chem Int Ed Engl.
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