dCK1α-1 | CK1α degrader | Probechem Biochemicals

Chemical Structure : dCK1α-1

Catalog No.: PC-23542Not For Human Use, Lab Use Only.

dCK1α-1 (LC-04-087) is a potent and selective CK1α-targeting molecular glue degrader with DC50 of 12 nM, Dmax of 90% in MOLM13 cells (72 h).

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Biological Activity

dCK1α-1 (LC-04-087) is a potent and selective CK1α-targeting molecular glue degrader with DC50 of 12 nM, Dmax of 90% in MOLM13 cells (72 h).

M.Wt	395.80
Formula	C19H14ClN5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-(5-(3-chloropyrazolo[1,5-a]pyrimidin-5-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

1. Lu Huang, et al. JACS Au. 2024 Nov 8;4(11):4423-4434.