dHTC3

Chemical Structure : dHTC3

Catalog No.: PC-25535Not For Human Use, Lab Use Only.

dHTC3 is a small molecule, FBXO3-dependent and BD1-specific BRD4 degrader, FBXO3 mediates BRD4 degradation by dHTC3.

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Biological Activity

dHTC3 is a small molecule, FBXO3-dependent and BD1-specific BRD4 degrader, FBXO3 mediates BRD4 degradation by dHTC3.

M.Wt	626.84
Formula	C31H42N6O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-butyl 2-((6S)-4-(4-((N-((2,2-diethylcyclopropyl)methyl)sulfamoyl)amino)phenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

1. Shaum JB, et al. bioRxiv [Preprint]. 2025 Sep 4:2024.09.30.615685.