Catalog No.: PC-62424Not For Human Use, Lab Use Only.
eIF4A3-IN-2 is an allosteric, selective, non-competitive eIF4A3 inhibitor with IC50 of 0.11 uM, exhibits noncompetitive inhibition with ATP or RNA and high selectivity for eIF4A3 over other helicases.
eIF4A3-IN-2 is an allosteric, selective, non-competitive eIF4A3 inhibitor with IC50 of 0.11 uM, exhibits noncompetitive inhibition with ATP or RNA and high selectivity for eIF4A3 over other helicases.
eIF4A3-IN-2 suppresses the helicase activity of eIF4A3 in an ATPase-dependent manner.
eIF4A3-IN-2 targets the exon junction complex (EJC) and suppresses monsense-mediated mRNA decay.
