miR544-IN-1 (SID 3712249) |CAS:522606-67-3 Probechem Biochemicals

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Chemical Structure : miR544-IN-1

CAS No.: 522606-67-3

miR544-IN-1 (SID 3712249, miR544 inhibitor 1)

Catalog No.: PC-62390Not For Human Use, Lab Use Only.

miR544-IN-1 (SID 3712249) is a selective small molecule inhibitor of miR-544 biogenesis.

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25 mg	$158	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

miR544-IN-1 (SID 3712249) is a selective small molecule inhibitor of miR-544 biogenesis.
miR544-IN-1 (SID 3712249) selectively inhibits production of the mature microRNA, sensitizes cells to 5-fluorouracil, and derepresses mRNAs affected by miR-544 in cellulo and in vivo, including boosting mTOR expression.
miR544-IN-1 (SID 3712249) reverses a tumor cell's physiological response to hypoxia.

Physicochemical Properties

M.Wt	323.404
Formula	C17H21N7
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1,8-diamino-3,6-di(pyrrolidin-1-yl)-2,7-naphthyridine-4-carbonitrile

References

1. Haga CL, et al. ACS Chem Biol. 2015 Oct 16;10(10):2267-76.

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miR544-IN-1 (SID 3712249, miR544 inhibitor 1)

Biological Activity

Physicochemical Properties

References

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