myomiRs-IN-1 |CAS:1392224-59-7 Probechem Biochemicals

Chemical Structure : myomiRs-IN-1

myomiRs-IN-1

Catalog No.: PC-62487Not For Human Use, Lab Use Only.

myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206.

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Biological Activity

myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206; upregulates miR-221/222 level and suppresses myoD protein expression in C2C12 cells; inhibits the differentiation of C2C12 cells.

Physicochemical Properties

M.Wt	533.58
Formula	C33H27NO6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-butyl (5-(8a-methoxy-3,8-dioxo-2-phenyl-2a,3,8,8a-tetrahydrocyclobuta[b]naphthalen-1-yl)quinolin-8-yl) carbonate

References

1. Tan SB, et al. Chem Biol. 2014 Oct 23;21(10):1265-70.

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myomiRs-IN-1

Biological Activity

Physicochemical Properties

References

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