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myomiRs-IN-1

Chemical Structure : myomiRs-IN-1

CAS No.: 1392224-59-7

myomiRs-IN-1

Catalog No.: PC-62487Not For Human Use, Lab Use Only.

myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206.
    myomiRs-IN-1 upregulates miR-221/222 level and suppresses myoD protein expression in C2C12 cells.
    myomiRs-IN-1 inhibits the differentiation of C2C12 cells.

    Physicochemical Properties

    M.Wt 533.58
    Formula C33H27NO6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    tert-butyl (5-(8a-methoxy-3,8-dioxo-2-phenyl-2a,3,8,8a-tetrahydrocyclobuta[b]naphthalen-1-yl)quinolin-8-yl) carbonate

    References

    1. Tan SB, et al. Chem Biol. 2014 Oct 23;21(10):1265-70.

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