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pdTp

Chemical Structure : pdTp

CAS No.: 2863-04-9

pdTp (3’, 5’-deoxythymidine bisphosphate;Thymidine 3',5'-diphosphate)

Catalog No.: PC-60906Not For Human Use, Lab Use Only.

A highly selective, small molecule inhibitor of the miRNA regulatory complex RISC subunit SND1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A highly selective, small molecule inhibitor of the miRNA regulatory complex RISC subunit SND1; inhibits hepatocellular carcinoma tumor formation without effects on body weight or liver function in human xenograft models of HCC.

Physicochemical Properties

M.Wt 402.189
Formula C10H16N2O11P2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-((phosphonooxy)methyl)tetrahydrofuran-3-yl dihydrogen phosphate

References

1. Jariwala N, et al. Cancer Res. 2017 Jun 15;77(12):3306-3316.

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