Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Neuropeptide Y Receptor-tBPC
tBPC

Chemical Structure : tBPC

CAS No.: 1942-71-8

Add to Favorites

tBPC (tert-butyl phenoxycyclohexanol)

Catalog No.: PC-61061Not For Human Use, Lab Use Only.

tBPC is a potent, selective neuropeptide Y (NPY) receptor Y4R positive allosteric modulator (EC50=5.1 uM) that potentiates Y4R activation in G-protein signaling and arrestin3 recruitment experiments.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    tBPC is a potent, selective neuropeptide Y (NPY) receptor Y4R positive allosteric modulator (EC50=5.1 uM) that potentiates Y4R activation in G-protein signaling and arrestin3 recruitment experiments.
    tBPC displyas no effect on Y1R, Y2R, and Y5R at 30 uM.
    tBPC selectively potentiates Y4R agonism initiated by pancreatic polypeptide (PP) in mouse descending colon mucosa preparations expressing native Y4R.

    Physicochemical Properties

    M.Wt 248.366
    Formula C16H24O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(4-(tert-butyl)phenoxy)cyclohexan-1-ol

    References

    1. Schubert M, et al. J Med Chem. 2017 Sep 14;60(17):7605-7612.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: