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trans-C75

Chemical Structure : trans-C75

CAS No.: 191282-48-1

trans-C75 (FASN inhibitor trans-C75, trans C75)

Catalog No.: PC-43006Not For Human Use, Lab Use Only.

trans-C75 is an enantiomer of FASN inhibitor C75, which is a synthetic, slow-binding inhibitor of mammalian FAS, binds to and inhibits mammalian FAS and inhibits fatty acid synthesis in human cancer cells (SKBR3 cells ID50=3.2 ug/mL).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

trans-C75 is an enantiomer of FASN inhibitor C75, which is a synthetic, slow-binding inhibitor of mammalian FAS, binds to and inhibits mammalian FAS and inhibits fatty acid synthesis in human cancer cells (SKBR3 cells ID50=3.2 ug/mL).

Physicochemical Properties

M.Wt 254.3221
Formula C14H22O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-, (2R,3S)-rel-

References

1. Kuhajda FP, et al. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3450-4.

2. Gao S, et al. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5628-33.

3. Thupari JN, et al. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502.

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