| Cat. No. |
Product Name |
Information |
| PC-35214 |
dBET23
|
dBET23 is a BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=50 nM) in cellular degradation assays.. |
| PC-35204 |
ZXH-3-26
|
ZXH-3-26 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC), shows activity exclusively on the BRD4 BD1 (DC50/5h=5 nM) and spares degradation of BRD2 or BRD3 in cellular degradation assays. |
| PC-35090 |
SNIPER(ER)-110
|
SNIPER(ER)-110 is a nongenetic IAP-dependent protein eraser (SNIPER) targeting estrogen receptor α (ERα), induces ERα degradation and induces apoptosis in MCF-7 human breast cancer cells. |
| PC-35040 |
PAC1
|
PAC1 (Compound PAC1) is a novel PROTAC antibody conjugate, more potent estrogen receptor-alpha (ERα) degrader compared to PROTAC without antibody conjugation.. |
| PC-35017 |
IBET151-VHL-PROTAC
|
IBET151-VHL-PROTAC is a novel PROTAC.. |
| PC-35013 |
JQ1-VHL-PROTAC
|
JQ1-VHL-PROTAC is a novel PROTAC synthesis.. |
| PC-60931 |
BETd-246
|
A potent, second-generation BET protein degrader that exhibits superior selectivity, potency and antitumor activity. |
| PC-60127 |
CM11
|
A homo-PROTAC, bivalent small-molecule dimerizer of the VHL E3 ubiquitin ligase to induce self-degradation. |
| PC-60096 |
Sirt2-PROTAC-1
|
A novel SirReal-based PROTAC that induces isotype-selective Sirt2 degradation (IC50=0.25 uM).. |
