α5IA | α5 GABAA receptor inverse agonist

Chemical Structure : α5IA

CAS No.: 215874-86-5

Catalog No.: PC-26748Not For Human Use, Lab Use Only.

α5IA (alpha5IA, L-822179) is a selective inverse agonist selective for α5 subunit-containing GABAA receptors, enhances cognition.

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Biological Activity

α5IA (alpha5IA, L-822179) is a selective inverse agonist selective for α5 subunit-containing GABAA receptors, enhances cognition.

M.Wt	362.35
Formula	C17H14N8O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(5-Methylisoxazol-3-yl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy][1,2,4]triazolo[3,4-a]phthalazine

1. Collinson N, et al. Psychopharmacology (Berl). 2006 Nov;188(4):619-28.

2. Stephens DN, et al. Eur J Pharmacol. 2005 Dec 5;526(1-3):240-50.

3. Dawson GR, et al. J Pharmacol Exp Ther. 2006 Mar;316(3):1335-45.