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(R)-BPO-27

Chemical Structure : (R)-BPO-27

CAS No.: 1415390-47-4

(R)-BPO-27 ((R)-BPO 27;(R)-BPO27)

Catalog No.: PC-45711Not For Human Use, Lab Use Only.

(R)-BPO-27, the R enantiomer of BPO-27, CFTR chloride conductance inhibitor with IC50 of 4 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

(R)-BPO-27, the R enantiomer of BPO-27, CFTR chloride conductance inhibitor with IC50 of 4 nM.
BPO-27 S enantiomer is inactive.

Physicochemical Properties

M.Wt 548.3416
Formula C26H18BrN3O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO

Chemical Name/SMILES

6H-Pyrimido[4',5':3,4]pyrrolo[2,1-c][1,4]benzoxazine-2-carboxylic acid, 6-(5-bromo-2-furanyl)-7,8,9,10-tetrahydro-7,9-dimethyl-8,10-dioxo-11-phenyl-, (6R)-

References

1. Snyder DS, et al. J Med Chem. 2011 Aug 11;54(15):5468-77.

2. Snyder DS, et al. ACS Med Chem Lett. 2013 May 9;4(5):456-459.

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