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(R)-Baclofen hydrochloride

Chemical Structure : (R)-Baclofen hydrochloride

CAS No.: 63701-55-3

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(R)-Baclofen hydrochloride (STX-209 hydrochloride)

Catalog No.: PC-45172Not For Human Use, Lab Use Only.

A derivative of the neurotransmitter GABA that acts as a GABAB receptor agonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A derivative of the neurotransmitter GABA that acts as a GABAB receptor agonist; also blocks α2δ subunit-containing voltage-dependent calcium channel (VDCC) with Ki of 156 uM; A neurotransmitter inhibitor by blocking the release of excitatory transmitters; serves as a central nervous system depressant and skeletal muscle relaxant.

Other Indication

Approved

Physicochemical Properties

M.Wt 250.1217
Formula C10H13Cl2NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride (1:1), (βR)-

References

1. Zvejniece L, et al. Pharmacol Biochem Behav. 2015 Oct;137:23-9.

2. Carter LP, et al. Pharmacol Ther. 2009 Jan;121(1):100-14.

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