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(R)-CE3F4

Chemical Structure : (R)-CE3F4

CAS No.: 1593478-56-8

(R)-CE3F4 (CE3F4 (R)-enantiomer)

Catalog No.: PC-63112Not For Human Use, Lab Use Only.

(R)-CE3F4 is a more potent, selective EPAC1 antagonist than the racemic CE3F4 and (S)-CE3F4, displays 10-fold selectivity for EPAC1 over EPAC2.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    (R)-CE3F4 is a more potent, selective EPAC1 antagonist than the racemic CE3F4 and (S)-CE3F4, displays 10-fold selectivity for EPAC1 over EPAC2.

    Physicochemical Properties

    M.Wt 351.01
    Formula C11H10Br2FNO
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-5,7-dibromo-6-fluoro-2-methyl-3,4-dihydroquinoline-1(2H)-carbaldehyde

    References

    1. Courilleau D, et al. Biochem Biophys Res Commun. 2013 Oct 25;440(3):443-8.

    2. Courilleau D, et al. J Biol Chem. 2012 Dec 28;287(53):44192-202.

    3. Brown LM, et al. J Biol Chem. 2014 Mar 21;289(12):8217-30.

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