| Cat. No. |
Product Name |
Information |
| PC-24626 |
RJG-2036
PTGR2 inhibitor
|
RJG-2036 is a potent, selective, covalent prostaglandin reductase 2 (PTGR2) inhibitor with IC50 of 100 nM (human PTGR2), covalently ligands the noncatalytic Y100 and Y265 residues located in the substrate binding pocket. |
| PC-24616 |
ORIC-533
CD73 inhibitor
|
ORIC-533 is a potent, selective, AMP-competitive and orally bioavailable ectonucleotidase CD73 inhibitor. |
| PC-24385 |
HEX-1
Pin1 inhibitor
|
HEX-1 is a valuable addition to the armamentarium against CRC, suppresses the proliferation of cancer cells and tumorigenesis via the inactivation and sensitization of PIN1. |
| PC-24354 |
Fisetin
NUF2 inhibitor
|
Fisetin is a small molecule inhibitor of NUF2, effectively inhibits PCa cell proliferation, shows antioxidant, anticancer, neuroprotection effects. |
| PC-24307 |
BPRPT0245
PTGR2 inhibitor
|
BPRPT0245 is a specific small-molecule inhibitor of prostaglandin reductase 2 (PTGR2) with IC50 of 8.92 nM, restores 15-keto-PGE2-dependent PPARγ trans-activation in HEK293T cells expressing recombinant PTGR2 with EC50 of 49.22 nM. |
| PC-24295 |
HOSU-53
DHODH inhibitor
|
HOSU-53 (JBZ-001) is a potent and selective inhibitor of DHODH with IC50 of 0.95 nM (hDHODH), exhibits potent antileukemic activity. |
| PC-24222 |
I3MT-3
3MST inhibitor
|
I3MT-3 (HMPSNE, 3MST inhibitor 3) is a potent, selective, cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 uM. |
| PC-24108 |
LIBX-A401
ACSL4 inhibitor
|
LIBX-A401 is a potent, selective inhibitor of Acyl-coenzyme A synthetase long-chain family member 4 (ACSL4) with IC50 of 0.38 uM, MST KD of 0.72 uM, with high selectivity over ACSL3 (IC50>50 uM), protects cells from ferroptosis. |
| PC-23912 |
TN2008
SRSF1 inhibitor
|
TN2008 is an effective serine arginine-rich splicing factor 1 (SRSF1) inhibitor with IC50 of 144 uM, exhibits high affinity for recombinant SRSF1 with Kd of 5.13 uM in SPR assays. |
| PC-23857 |
VK-2019
EBNA1 inhibitor
|
VK-2019 is a selective small molecule inhibitor of Epstein-Barr virus Nuclear Antigen 1 (EBNA1), reduces EBV genome copy number and viral gene expression in EBV-positive nasopharyngeal carcinoma. |
| PC-23850 |
ALT-007
Serine palmitoyltransferase inhibitor
|
ALT-007 is a potent, selective and orally bioavailable inhibitor of serine palmitoyltransferase (SPT) with enzyme IC50 of 0.54 nM. |
| PC-23833 |
EOS301984
ENT1 inhibitor
|
EOS301984 (EOS-984) is a potent, selective equilibrative nucleoside transporter 1 (ENT1) antagonist with IC50 of 339.6 nM (human ENT1), 150-fold selectivity for ENT1 versus ENT2. |
