| Cat. No. |
Product Name |
Information |
| PC-27508 |
Tazbentetol
Synaptic regenerative agent
|
Tazbentetol (SPG302) is a pegylated benzothiazole derivative and synaptic regenerative small molecule, targets the cytoskeleton and induces the formation of new glutamatergic synapses. |
| PC-27505 |
JXL069
MPC inhibitor
|
Suvomipic (JXL069) is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 42.8 nM. |
| PC-27499 |
AKBA
MAT2A inhibitor
|
AKBA is a bioactive boswellic acid found in frankincense and allosteric, specific inhibitor of methionine adenosyltransferase 2A (MAT2A) with MST Kd of 129 nM, shows anti-inflammatory and anti-cancer properties. |
| PC-27497 |
SARM1 inhibitor MY-13B
SARM1 inhibitor
|
SARM1 inhibitor MY-13B is a stereoselective, covalent SARM1 inhibitor, site-specifically engage C311 in SARM1. |
| PC-27492 |
Rexipictor
Polycystin-1 corrector
|
Rexipictor (VX-407) is a first-in-class small molecule Polycystin-1 (Polycystin 1, PC1, PKD1) corrector, corrects inappropriate PC1 folding to abate cystogenesis and eGFR decline, shows potential for treatment of autosomal dominant polycystic kidney disease (ADPKD). |
| PC-27442 |
FSG67
GPAT inhibitor
|
FSG67 is a small molecule mitochondrial glycerol-3-phosphate acyltransferase (mitochondrial GPAT, GPAM) inhibitor with IC50 30.2 μM for total mitochondrial GPAT and 42.1 μM for GPAT1. |
| PC-27273 |
PBITE-1
ERG PNT domain binder
|
PBITE-1 is a small molecule that selectively binds ERG N-terminal Pointed (PNT) domain with Kd of 264 uM in BLI assays, directly engages ERG, selectively inhibits proliferation and invasion, and induces apoptosis in ERG-driven prostate and hematologic malignancies. |
| PC-27212 |
A2ti-2
S100A10-ANXA2 inhibitor
|
A2ti-2 (S100A10-ANXA2 heterotetramer inhibitor-2) is a specific small molecule Annexin A2 (ANXA2) inhibitor, inhibits Annexin A2-S100A10 protein interaction with IC50 of 230 nM (Annexin A2/S100A10 heterotetramer (A2t)), blocks HPV16 infection and entry into HeLa cells. |
| PC-27202 |
SGM-3
Striga germination inhibitor, ShHTL7 inhibitor
|
Striga germination modulator-3 (SGM-3) is a potent, selective germination inhibitor for Striga hermonthica, selectively binds to ShHTL7 and shows inhibitory activity against YLG hydrolysis by ShHTL7 with IC50 of 2.3 uM. |
| PC-27201 |
KK023-N1
Striga germination inhibitor, ShHTL7 inhibitor
|
KK023-N1 is a potent, specific Striga germination inhibitor, blocks the hydrolysis activity of S. hermonthica HYPO-SENSITIVE TO LIGHT 7 (ShHTL7) with IC50 of 1.78 uM, does not affect rice (Oryza sativa) SL receptor DWARF14 (OsD14). |
| PC-27105 |
A2ti-1
S100A10-ANXA2 inhibitor
|
A2ti-1 (S100A10-ANXA2 heterotetramer inhibitor-1) is a specific small molecule Annexin A2 (ANXA2) inhibitor, inhibits Annexin A2-S100A10 protein interaction with IC50 of 24 uM (Annexin A2/S100A10 heterotetramer (A2t)). |
| PC-27102 |
TRMT10C agonist TM3
TRMT10C agonist
|
TRMT10C agonist TM3 is a small molecule agonist of tRNA methyltransferase 10C (TRMT10C), exhibits direct binding with a dissociation constant (Kd) of 2.6 uM in SPR assays, promotes osteoblast differentiation and protects against osteoporosis. |
