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Cat. No. Product Name Information
PC-63313

IP6K1 inhibitor TNP

IP6K inhibitor

IP6K1 inhibitor TNP is a potent, selective inositol hexakisphosphate kinase IP6K with IC50 of 0.47 uM (IP6K1), does not inhibit either human or yeast Vip/PPIP5K.
PC-63307

TLSC702

hGLO I inhibitor

TLSC702 is a novel potent inhibitor of human glyoxalase I (hGLO I) with IC50 of 2.0 uM.
PC-63266

ABL127

PME-1 inhibitor

ABL127 (ML174) is a potent, selective, covalent inhibitor of protein methylesterase 1 (PME-1) with IC50 of 10 nM.
PC-63262

(R)-HZ05

DHODH inhibitor

(R)-HZ05 is a potent DHODH inhibitor with IC50 of 11 nM, accumulates cancer cells in S-phase, increases p53 synthesis, and synergizes with an inhibitor of p53 degradation (Nutlin-3a) to reduce tumor growth in vivo..
PC-63261

HZ05

DHODH inhibitor

HZ05 is a potent DHODH inhibitor with IC50 of 32 nM, accumulates cancer cells in S-phase, increases p53 synthesis, and synergizes with an inhibitor of p53 degradation (Nutlin-3a) to reduce tumor growth in vivo..
PC-63249

JBSNF-000088

NNMT inhibitor

JBSNF-000088 (6-Methoxynicotinamide) is a small molecule nicotinamide analog that inhibits Nicotinamide N-methyltransferase (NNMT) with IC50 of 1.8, 2.8 and 5.0 µM for human, monkey and mouse NNMT, respectively.
PC-63248

BI-1935

sEH inhibitor

BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM.
PC-63244

Bractoppin

Bractoppin is a potent, small-molecule chemical inhibitor that specific selectively blocks phosphopeptide recognition by the BRCA1 tBRCT domain with binding IC50 of 74 nM.
PC-43424

NXY-059

NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo.
PC-43398

Avasimibe

ACAT inhibitor

Avasimibe (CI-1011, PD-148515) is a potent, selective inhibitor of acyl-CoA: cholesterol O-acyl transferase (ACAT) with IC50 of 60 nM.
PC-43358

SMND-309

SMND-309 is a derivate of salvianolic acid B, attenuates apoptosis and ameliorates mitochondrial energy metabolism in rat cortical neurons.
PC-43319

Laquinimod

Immunoregulator

Laquinimod (ABR-215062) is an immunoregulator derived from Linomide, has been shown to completely inhibit the development of murine acute experimental autoimmune encephalomyelitis (EAE).

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