| Cat. No. |
Product Name |
Information |
| PC-20890 |
Lalistat-1
LAL inhibitor
|
Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase. |
| PC-20889 |
Lalistat-2
LAL inhibitor
|
Lalistat-2 (L-stat) is a specific inhibitor of lysosomal acid lipase (LAL) with IC50 of 152 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase. |
| PC-20883 |
NCI-41356
CRYAB inhibitor
|
NCI-41356 is a small molecular inhibitor of αB-crystallin (CRYAB, HSPB5), significantly reducesthe interaction between CRYAB and VEGF165. |
| PC-20871 |
NVP-231
CerK inhibitor
|
NVP-231 (NVP231) is a potent, specific, and reversible ceramide kinase (CerK) inhibitor with IC50 of 12 nM. |
| PC-20868 |
Imanixil
LDLR inducer
|
Imanixil (HOE402) is a small molecule inducer of the LDL receptor (LDLR), HOE402 is a potent cholesterol-lowering compound, inhibits VLDL production. |
| PC-20866 |
ARUK200282
PI5P4Kα inhibitor
|
ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ. |
| PC-20859 |
LI-2242
IP6K inhibitor
|
LI-2242 is a potent pan-IP6K inhibitor with IC50 of with IC50 of 31, 42 and 8.1 nM for IP6K1, IP6K2 and IP6K3, respectively. |
| PC-20847 |
C902
LIN28 inhibitor
|
C902 is a small-molecule inhibitor targeting LIN28-let-7 interaction, shows dose-dependent inhibition in an EMSA validation assay with IC50 of 5 uM. |
| PC-20846 |
CC-410
NNMT inhibitor
|
CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT). |
| PC-20842 |
GCN2iA
GCN2 inhibitor
|
GCN2iA is a potent seletive inhibitor of general control nonderepressible 2 (GCN2) with IC50 of 4.0 nM. |
| PC-20837 |
SRP-001
Analgesic agent
|
SRP-001 is a non-opioid and non-hepatotoxic small molecule ApAP analog, induces analgesia via N-arachidonoylphenolamine (AM404) formation, and generates higher amounts of AM404 than ApAP. |
| PC-20828 |
LAG-3 inhibitor SA-15-P
LAG-3 inhibitor
|
LAG-3 inhibitor SA-15-P is a small molecule dual inhibitor of LAG-3/MHCII and LAG-3/FGL1 interactions with IC50 of 4.21 and 6.52 uM, respectively. |
