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Cat. No. Product Name Information
PC-61009

DS-1040

TAFIa inhibitor

DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa.
PC-60959

NGI-1

OST inhibitor

NGI-1 (ML414) is a potent, cell-permeable oligosaccharyltransferase (OST) inhibitor with IC50 of 1.1 uM.
PC-60880

ZINC 39395747

CYB5R3 inhibitor

ZINC 39395747 is a novel potent derivative of propylthiouracil that functions as a cell-active inhibitor of cytochrome b5 reductase 3 (CYB5R3) with IC50 of 9.14 uM.
PC-50007

BRD10330

IL-10 inducer

BRD10330 (BRD-10330) is a small molecule that upregulates IL-10 production in BMDCs.
PC-60849

ADDA 5

Cytochrome c oxidase inhibitor

ADDA 5 is a specific, non-competitive, small molecule cytochrome c oxidase (CcO or complex IV) inhibitor with IC50 of 18.93 uM (CcO from human glioma).
PC-60717

TK05

LTC4S inhibitor

TK05 is a potent and selective inhibitors of leukotriene C4 synthase (LTC4S) with IC50 of 95 nM, Ki of 6 nM.
PC-60714

PRD125

ACAT2 inhibitor

PRD125 is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2, ACAT2) with IC50 of 11.8 nM, >6,000-fold selectivity over ACAT1.
PC-60694

LX2931

S1P lyase inhibitor

LX-2931 (LX2931) is a potent, selective and orally bioavailable S1P lyase (S1PL) inhibitor.
PC-60693

S1P Lyase inhibitor 31

S1PL inhibitor

S1P Lyase inhibitor 31 is a potent, selective and orally bioavailable S1P lyase (S1PL) inhibitor with enzyme IC50 of 44 nM, cell IC50 of 110 nM.
PC-60680

ES936

NQO1 inhibitor

ES936 is a potent, specific mechanism-based human NAD(P)H: quinone oxidoreductase 1 (NQO1) inhibitor that demonstrates efficient inactivation of NQO1 at 100 nM in in cellular systems.
PC-60677

AR03

APE1 inhibitor

AR03 (BMH-23, AR03, Ape1 repair inhibitor 03) is a novel small molecule inhibitor of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) endonuclease activity with IC50 of 5 uM.
PC-60661

PD 404182

DDAH1 inhibitor

PD 404182 (PD404182, PD-404182) is a heterocyclic iminobenzothiazine derivative with antimicrobial and anti-inflammatory properties, a potent inhibitor of human DDAH1 activity (IC50=9 uM) and elevates cellular ADMA levels.

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