| Cat. No. |
Product Name |
Information |
| PC-70251 |
AUDA-BE
sEH inhibitor
|
AUDA-BE is the prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively. |
| PC-70250 |
Cysmethynil
ICMT inhibitor
|
Cysmethynil is a selective small-molecule inhibitor of tisoprenylcysteine carboxyl methyltransferase (Icmt) with IC50 <200 nM. |
| PC-70248 |
Migrastatin
Cancer migration inhibitor
|
Migrastatin is a biologically active natural product isolated from Streptomyces that has been shown to inhibit tumor cell migration. |
| PC-70247 |
C2-8
polyQ aggregation inhibitor
|
C2-8 is a small molecule inhibitor of polyglutamine (polyQ) aggregation in Huntington's disease neurons. |
| PC-70238 |
NSC 65828
Angiogenin inhibitor
|
NSC 65828 (NCI65828) is a small-molecule inhibitor of the ribonucleolytic activity of human angiogenin with Ki of 81 uM. |
| PC-70343 |
Endosomal trafficking inhibitor EGA
Endosomal trafficking inhibitor
|
EGA is a potent anthrax lethal toxin entry inhibitor with IC50 of 1.7 uM, inhibits endosomal trafficking pathways exploited by multiple toxins and viruses. |
| PC-70338 |
XIB-4035
GFRα-1 agonist
|
(E)-Aminoquinol (XIB-4035) is a nonpeptidyl small molecule agonist of GDNF family receptor α1 (GFRα-1). |
| PC-70335 |
TRAF-STOP 6877002
CD40-TRAF6 inhibitor
|
TRAF-STOP 6877002 (SMI-6877002) is a small molecule inhibitor that blocks the interaction between CD40 and TRAF6 (TRAF-STOP), while leaving CD40-TRAF2/3/5 interactions intact, thereby preserving CD40-mediated immunity. |
| PC-70334 |
SC57461A
LTA4H inhibitor
|
SC57461A (SC 57461A) is a potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM. |
| PC-70333 |
ARM-1
LTA4H inhibitor
|
ARM-1 is a novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM. |
| PC-70326 |
Seriniquinone
Dermcidin inhibitor
|
Seriniquinone (S 747855) is a melanoma-selective anticancer agent (IC50=30 nM, Malme-3M cell line), induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin. |
| PC-70315 |
Endosidin 2
Endosomal trafficking inhibitor
|
Endosidin 2 (Endosidin2, ES2) is a small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking. |
