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Chemical Structure : PDMP hydrochloride
Catalog No.: PC-61425Not For Human Use, Lab Use Only.
PDMP hydrochloride is a ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest.
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PDMP hydrochloride is a ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest.
| M.Wt | 427 | |
| Formula | C23H38N2O3 • HCl | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Abe A, et al. J Lipid Res. 1995 Mar;36(3):611-21.
2. Rani CS, et al. J Biol Chem. 1995 Feb 10;270(6):2859-67.
3. Bielawska A, et al. J Biol Chem. 1996 May 24;271(21):12646-54.
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