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PDMP hydrochloride

Chemical Structure : PDMP hydrochloride

CAS No.: 73257-80-4

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PDMP hydrochloride (Glucosylceramide synthase inhibitor, GCS inhibitor)

Catalog No.: PC-61425Not For Human Use, Lab Use Only.

PDMP hydrochloride is a ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PDMP hydrochloride is a ceramide analog that inhibits glucosylceramide synthase (GCS), reduces the synthesis of sphingosine and its derivatives, increases cellular ceramide, and induces cell cycle arrest.

    Physicochemical Properties

    M.Wt 427
    Formula C23H38N2O3 • HCl
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    Decanamide, N-[2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, hydrochloride (9CI)

    References

    1. Abe A, et al. J Lipid Res. 1995 Mar;36(3):611-21.

    2. Rani CS, et al. J Biol Chem. 1995 Feb 10;270(6):2859-67.

    3. Bielawska A, et al. J Biol Chem. 1996 May 24;271(21):12646-54.

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