| Cat. No. |
Product Name |
Information |
| PC-27631 |
17β-HSD13-IN-1
17β-HSD13 inhibitor
|
17β-HSD13-IN-1 is a potent, selective hydroxysteroid 17-β-dehydrogenase 13 (17β-HSD13) inhibitor with cell IC50 of 14 nM, has >3000-fold seletivity over 17β-HSD1. |
| PC-27624 |
Transketolase-IN-1
Transketolase inhibitor
|
Transketolase-IN-1 (Compound 5aw) is a small molecule Transketolase (TK, EC 2.2.1.1) inhibitor, tightly binds with the enzyme At TK, exhibits potent postemergence herbicidal activity. |
| PC-27609 |
N-arachidonylglycine
GPR18 agonist, GPR92 agonist
|
N-Arachidonylglycine (NAGly, NA-Gly) is a carboxylic analog of the endocannabinoid anandamide (AEA) and endogenous ligand/agonist of GPR18 with EC50 of 44.5 nM, also is a endogenous agaonist of orphan G protein-coupled receptor GPR92 with EC50 of 4.47 uM. |
| PC-27608 |
Protoporphyrin IX disodium
CAS 50865-01-5
|
Protoporphyrin IX disodium (Proto IX, PPIX) is the branch point in chloroplast tetrapyrrole biosynthesis, also acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage, also is a dye content for fluorescence spectroscopic assays. |
| PC-27607 |
Protoporphyrin IX
CAS 553-12-8
|
Protoporphyrin IX (Proto IX, PPIX) is the branch point in chloroplast tetrapyrrole biosynthesis, also acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage, also is a dye content for fluorescence spectroscopic assays. |
| PC-27606 |
N-methyl protoporphyrin IX
FECH inhibitor
|
N-methyl protoporphyrin IX (NMPP, N-MPP) is a selective Ferrochelatase (FECH) antagonist with Ki app pf 3 nM, inhibits heme synthesis, also inhibits nitric oxide synthase isoforms nNOS, iNOS, and eNOS with IC50 of 5-8 uM. |
| PC-27605 |
AM404
Anandamide transport inhibitor
|
AM404 is a seletive inhibitor of anandamide transport with IC50 of 2.2 uM, does not activate cannabinoid receptors or inhibit anandamide hydrolysis. |
| PC-27602 |
Pyridoxal Isonicotinoyl Hydrazone
Ferrochelatase inhibitor, Iron chelator
|
Pyridoxal isonicotinoyl hydrazone (PIH) is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions. |
| PC-27597 |
Afegostat tartrate
Glycosidase inhibitor
|
Afegostat tartrate (Isofagomine D-Tartrate, AT2101) is a broad spectrum inhibitor of glycosidases, inhibits beta-glucosidase, glucoamylase, isomaltase, and alpha-glucosidase, specifically and reversibly binds lysosomal hydrolase acid β-glucosidase (GCase) in the ER with high affinity. |
| PC-27582 |
dPTBD
Cuproptosis inducer
|
dPTBD is a copper ionophore and cuproptosis inducer, promotes intracellular copper accumulation particularly in the mitochondria, leading to metabolic disruption and cuproptotic cell death, exhibits significant antitumor efficacy in KRAS-driven cancers both in vitro and in vivo. |
| PC-27560 |
EZ-482
ApoE ligand, ApoE inhibitor
|
EZ-482 is a small molecule ligand of Apolipoprotein E (ApoE), binds to the C-terminal domains of both ApoE3 and ApoE4 with KD of approximately 8 μM, blocks heparin binding to the N-terminal domain. |
| PC-27550 |
Rhoifolin
CAS 17306-46-6
|
Rhoifolin is a natural flavonoid with anti-inflammatory and antiparasitic potential, is a a direct potassium channel modulatory factor 1 (KCMF1) binder that stabilizes AMPKα and ameliorates MASLD, also inhibits the specific binding site of ALDH2-PKCδ, significantly increases chemosensitivity. |
