| Cat. No. |
Product Name |
Information |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-28509 |
Edaravoside
Free radical scavenger
|
Edaravoside is a free radical scavenger investigated for neuroprotective effects in ischemic stroke. |
| PC-28503 |
CD38 inhibitor 16
CD38 inhibitor
|
CD38 inhibitor 16 is a potent, selective and brain-penetrant CD38 inhibitor with IC50 of 2.71 nM and 1.94 nM for mCD38 and hCD37 respectively. |
| PC-28493 |
Compound 9787
RpS5 modulator
|
Compound 9787 is a specific small molecule targeting 30S ribosomal protein S5 (RpS5), enhances translational fidelity at concentrations does not impact the overall rate of protein synthesis, reverses rifampicin tolerance. |
| PC-28461 |
LCL521 dihydrochloride
Acid ceramidase inhibitor
|
LCL521 dihydrochloride (1,3-di-DMG-B13) is a small molecular inhibitor of acid ceramidase (ACDase), a lysosomotropic inhibitor with anticancer activity. |
| PC-28458 |
Dafaglitapin
ALCAT1 inhibitor
|
Dafaglitapin (Juvenatin, Juve) is a potent and highly specific acyl-coenzyme A:lysocardiolipin acyltransferase-1 (ALCAT1) inhibitor with IC50 of 3 nM. |
| PC-28422 |
PF-429242
S1P inhibitor
|
PF-429242 (PF429242) is a potent, selective, reversible and competitive inhibitor of proprotein convertase SREBP site 1 protease (S1P, Subtilisin kexin isozyme-1/SKI-1, MBTPS1) with IC50 of 170 nM. |
| PC-28412 |
F35-303
BEX4-XRCC5 inhibitor
|
F35-303 is a small molecule inhibitor of BEX4-XRCC5 interaction with IC50 of 2.39 uM in Huh6 cells, exhibits binding affinity for XRCC5 with SPR KD of 0.751 uM, suppresses NHEJ repair activity and reduces HB cells cell viability, inhibits cisplatin resistance. |
| PC-28396 |
α-Fluoromethylhistidine dihydrochloride
Histidine decarboxylase inhibitor
|
alpha-fluoromethylhistidine (α-FMH) is an orally active, irreversible histamine producing enzyme histidine decarboxylase (HDC) inhibitor with IC50 of 1-2 uM for soluble histidine decarboxylase preparations, inhibits histamine synthesis with IC50 of 0.2 uM in intact cell suspensions. |
| PC-28391 |
F-53B
CAS 73606-19-6
|
F-53B (6:2 Cl-PFAES) is a 6:2 chlorinated polyfluorinated ether sulfonate is an alternative to perfluorooctanesulfonate (PFOS) in electroplating industry, significantly inhibits the growth of zebrafish and induces reproductive toxicity. |
| PC-28366 |
MMS-350
Antifibrotic
|
MMS-350 is a DMSO analog and bis-oxetanyl sulfoxide that acts as a radiation protector and mitigator, reduces pulmonary fibrosis induced by different triggers, reduces levels of extracellular matrix proteins, the activation of fibroblasts, and the induction of pro-fibrotic factors. |
