| Cat. No. |
Product Name |
Information |
| PC-27357 |
DHODH inhibitor HL6
DHODH inhibitor
|
DHODH inhibitor HL6 is a potent, CoQ-competitive DHODH inhibitor with Ki of 2.39 nMand IC50 of 5.29 nM (recombinant human DHODH), disrupts WDR77 stabilization, thereby attenuating PRMT5/WDR77-dependent AKT signaling in PIK3CA-mutant CRC. |
| PC-27356 |
Hesperetin
520-33-2
|
Hesperidin (Hesperetin 7-rutinoside) is a flavanone glycoside isolated from citrus fruits, shows numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects, antitumor and antiallergic activities. |
| PC-27355 |
KY-455
ACAT inhibitor
|
KY-455 is an anti-oxidative ACAT inhibitor, inhibits rabbit intestinal, hepatic, macrophage and adrenal ACAT with IC50 of 0.4, 0.9, 2.9 and 4.1 uM, respectively. |
| PC-27348 |
ST029248
Mast cell activator
|
ST029248 is a small molecule mast cell activator (MCA) with 50% degranulation levels (MCD50) of 2.9 uM, promotes de novo synthesis of cytokines and induce the release of eicosanoids from MCs. |
| PC-27347 |
ST026567
Mast cell activator
|
ST026567 is a small molecule mast cell activator (MCA), induces mouse BMMCs degranulation achieving 50% degranulation levels (MCD50) of 24.6 uM, promotes de novo synthesis of cytokines and induce the release of eicosanoids from MCs. |
| PC-27346 |
VAP-1185
Mast cell activator
|
VAP-1185 is a potent small molecule mast cell activator (MCA), induces mouse BMMCs degranulation, promotes a Th1-biased immune response when combined with TLR9 agonist CpG. |
| PC-27345 |
ST101036
Mast cell activator
|
ST101036 is a small molecule mast cell activator (MCA), induces mouse BMMCs degranulation about 91% at 100 uM, and 38% in human LAD2 cells, promotes de novo synthesis of cytokines and induce the release of eicosanoids from mouse MCs. |
| PC-27344 |
OGG1 agonist F01
OGG1 agonist
|
OGG1 agonist F01 is a potent small-molecule agonist with EC50 of 9.1 uM with 8-oxoGua-containing DNA substrate. |
| PC-27343 |
OGG1 agonist F51
OGG1 agonist
|
OGG1 agonist F51 is a potent small-molecule agonist, protects against PQ-induced cytotoxicity in Kasumi-1 cells, binds to catalytic-site rather than allosteric binding. |
| PC-27321 |
C67-47
PGK1 inhibitor
|
C67-47 is a potent and orally efficacious Phosphoglycerate kinase 1 (PGK1) inhibitor, binds strongly to PGK1 with a dissociation constant (Kd) of 63 nM, exhibits potent antiproliferative effects in pancreatic cancer cells. |
| PC-27319 |
G2A antagonist 65
GPR132 antagonist
|
G2A antagonist 65 is a potent, selective G protein coupled receptor 132 (GPR132 or G2A) antagonist with IC50 of 0.69 uM, prevents the 9-HODE-mediated sensitization of capsaicin-induced TRPV1 responses in primary sensory neurons. |
| PC-27318 |
G2A antagonist 31
GPR132 antagonist
|
G2A antagonist 31 is a potent, selective G protein coupled receptor 132 (GPR132 or G2A) antagonist with IC50 of 0.33 uM. |
