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Cat. No. Product Name Information
PC-38905

(R)-HTS-3

LPCAT3 inhibitor

(R)-HTS-3 is a small-molecule inhibitor of lysophosphatidylcholine acyltransferase 3 (LPCAT3) with IC50 of 0.09 uM, an integral membrane acyltransferase in the Lands cycle responsible for generating C20:4 phospholipids.
PC-38904

CIB-3b

TRBP-Dicer inhibitor

CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
PC-38900

XST-20

FOXM1 inhibitor

XST-20 is a small molecule selectively targeting FOXM1 DNA-binding domain (DBD) with SPR Kd of 20 uM, effectively suppresses FOXM1 transcriptional activities and inhibits ovarian cancer cell proliferation.
PC-38889

Alrefimotide

Alrefimotide (Telomerase reverse transcriptase 660-689 peptide antigen).
PC-38841

UK5099

MPC blocker

UK5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC), inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria with IC50 of 50 nM.
PC-38837

Silibinin A

Silibinin is a flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities.
PC-38797

ERX-41

LIPA inhibitor

ERX-41 is a small molecule that binds to lysosomal acid lipase A (LIPA), and induces endoplasmic reticulum (ER) stress resulting in cell death, blocks proliferation of ER-α⁺ BC cells and TNBC cells in vitro.
PC-38788

Sarcomere inhibitor W7

Sarcomere inhibitor

Sarcomere inhibitor W7 is a small-molecule sarcomere Ca2+ desensitizer, decreases intact cardiac myocyte contractility in a Ca2+ transient amplitude-independent manner.
PC-38785

EVT-701

Mitochondrial complex 1 inhibitor

EVT-701 is a highly potent, selective, and safe mitochondrial complex 1 (MC1) inhibitor, reduces NADH abundance with IC50 of 300 nM.
PC-38779

LCL521

Acid ceramidase inhibitor

LCL521 is a small molecular inhibitor of acid ceramidase (ACDase), a lysosomotropic inhibitor with anticancer activity.
PC-38777

STK793590

DJ-1/PARK7 inhibitor

STK793590 (DJ-1/PARK7 inhibitor 15) is a potent inhibitor of the Parkinson's disease associated protein DJ-1/PARK7 with Kd/IC50 of 0.1/0.28 uM, respectively.
PC-38774

PXS-5505

pan-LOX inhibitor

PXS-5505 is an orally available, small-molecule, irreversible inhibitor of all lysyl oxidases (pan-LOX) family members, with potential antifibrotic activity.

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