| Cat. No. |
Product Name |
Information |
| PC-21865 |
PCiB-3
Phosphatidylcholine synthesis inhibitor
|
PCiB-3 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 0.4 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2. |
| PC-21864 |
PCiB-2
Phosphatidylcholine synthesis inhibitor
|
PCiB-2 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 2.0 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2, induces mitochondrial division. |
| PC-21863 |
PCiB-1
Phosphatidylcholine synthesis inhibitor
|
PCiB-1 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 7.0 uM, inhibits phosphatidylethanolamine (PE) transport from mitochondria to the endoplasmic reticulum (ER), induces mitochondrial division. |
| PC-21828 |
ZNF207 inhibitor C16
ZNF-207 inhibitor
|
ZNF207 inhibitor C16 is a small molecule inhibitor of Zinc Finger Protein 207 (ZNF207) with binding KD of 67 nM (SPR assays), inhibits glioma cancer cell stemness. |
| PC-21825 |
EC5026
sEH inhibitor
|
EC5026 is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain. |
| PC-21824 |
AR9281
sEH inhibitor
|
AR9281 (APAU) is a potent, selective and orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 8 nM and 3 nM for human and mouse sEH enzyme, respectively. |
| PC-21810 |
Tpm1.8/9-3
Tpm1.8/9 inhibitor
|
Tpm1.8/9-3 (CID 18973468) is a specific small molecule inhibitor of Tpm1.8/9, antagonizes Tpm1.8/9's effects on EMT, Wnt signaling, and resistance to chemotherapy. |
| PC-21809 |
Tpm1.8/9-1
Tpm1.8/9 inhibitor
|
Tpm1.8/9-1 (CID 6494468) is a specific small molecule inhibitor of Tpm1.8/9, antagonizes Tpm1.8/9's effects on EMT, Wnt signaling, and resistance to chemotherapy. |
| PC-21807 |
RU-NT-206
Ricin inhibitor
|
RU-NT-206 is a small molecule inhibitor targeting the P-stalk binding pocket of ricin toxin A subunit (RTA) with IC50 of 7 uM, inhibits catalytic activity and protects cells against ricin and Stx2 holotoxins. |
| PC-21805 |
SPI-1477
Spt5-Pol II inhibitor
|
SPI-1477 (SPI-77) is a small molecule Spt5-Pol II complex inhibitor (SPI), selectively lowers mutant huntingtin gene (Htt) mRNA level with IC50 of 0.1 nM, without affecting WT Htt. |
| PC-21804 |
SPI-0324
Spt5-Pol II inhibitor
|
SPI-0324 (SPI-24) is a small molecule Spt5-Pol II complex inhibitor (SPI), selectively lowers mutant huntingtin gene (Htt) mRNA level with IC50 of 0.52 uM, without affecting WT Htt. |
| PC-21800 |
LY3509754
IL-17A inhibitor
|
LY3509754 is a potent, selective and oral small molecule inhibitor of IL-17A with high binding potency(KD=2.14 nM), dose-dependently prevents human IL-17A and IL-17AF from binding human IL-17RA. |
