| Cat. No. |
Product Name |
Information |
| PC-28598 |
N-Acetylcysteine amide
Antioxidant
|
N-acetylcysteine amide (NACA) is a blood-brain-barrier permeable antioxidant and glutamate-modulating compound, reduces ROS production and shows neuroprotective activity. |
| PC-28595 |
MR-409
GHRH agonist
|
MR-409 (MR 409, MR409) is a synthetic GHRH analogue and growth hormone-releasing hormone receptor (GHRHR) agonist with binding IC50 of 1.01 nM in membrane GHRHR of human pituitary cells, exhibits high growth hormone-releasing potency. |
| PC-28594 |
MP-002
FKBP12 ligand
|
MP-002 (AHK2) is a triazole-based FKBP12 ligand, competes with rapamycin for the FKBP12 binding pocket, stabilizing the FKBP12/RyR interaction, rescues multiple premature aging phenotypes in dyotonic dystrophy type 1 (DM1) models. |
| PC-28593 |
ERO1α inhibitor I29
ERO1α inhibitor
|
ERO1α inhibitor I29 is a specific small molecule inhibitor of Endoplasmic reticulum oxidoreductin 1 alpha (ERO1A, ERO1α) with IC50 of 2.6 uM, inhibits ERO1-driven triple-negative breast cancer and SEPN1-related myopathy, phenocopies ERO1α genetic deletion and enhances efficacy of anti-PD-1 therapy. |
| PC-28509 |
Edaravoside
Free radical scavenger
|
Edaravoside is a free radical scavenger investigated for neuroprotective effects in ischemic stroke. |
| PC-28503 |
CD38 inhibitor 16
CD38 inhibitor
|
CD38 inhibitor 16 is a potent, selective and brain-penetrant CD38 inhibitor with IC50 of 2.71 nM and 1.94 nM for mCD38 and hCD37 respectively. |
| PC-28493 |
Compound 9787
RpS5 modulator
|
Compound 9787 is a specific small molecule targeting 30S ribosomal protein S5 (RpS5), enhances translational fidelity at concentrations does not impact the overall rate of protein synthesis, reverses rifampicin tolerance. |
| PC-28461 |
LCL521 dihydrochloride
Acid ceramidase inhibitor
|
LCL521 dihydrochloride (1,3-di-DMG-B13) is a small molecular inhibitor of acid ceramidase (ACDase), a lysosomotropic inhibitor with anticancer activity. |
| PC-28458 |
Dafaglitapin
ALCAT1 inhibitor
|
Dafaglitapin (Juvenatin, Juve) is a potent and highly specific acyl-coenzyme A:lysocardiolipin acyltransferase-1 (ALCAT1) inhibitor with IC50 of 3 nM. |
| PC-28422 |
PF-429242
S1P inhibitor
|
PF-429242 (PF429242) is a potent, selective, reversible and competitive inhibitor of proprotein convertase SREBP site 1 protease (S1P, Subtilisin kexin isozyme-1/SKI-1, MBTPS1) with IC50 of 170 nM. |
| PC-28412 |
F35-303
BEX4-XRCC5 inhibitor
|
F35-303 is a small molecule inhibitor of BEX4-XRCC5 interaction with IC50 of 2.39 uM in Huh6 cells, exhibits binding affinity for XRCC5 with SPR KD of 0.751 uM, suppresses NHEJ repair activity and reduces HB cells cell viability, inhibits cisplatin resistance. |
| PC-28396 |
α-Fluoromethylhistidine dihydrochloride
Histidine decarboxylase inhibitor
|
alpha-fluoromethylhistidine (α-FMH) is an orally active, irreversible histamine producing enzyme histidine decarboxylase (HDC) inhibitor with IC50 of 1-2 uM for soluble histidine decarboxylase preparations, inhibits histamine synthesis with IC50 of 0.2 uM in intact cell suspensions. |
