| Cat. No. |
Product Name |
Information |
| PC-42293 |
EC330
LIF inhibitor
|
EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor, LIFR) inhibitor. |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-45513 |
HQ-415
Metal chelator, TDP-43 modulator
|
HQ-415 is a derivative of 8-hydroxyquinoline that has selectivity for rescuing the distinct toxicities caused by the expression of TDP-43 with EC50 of 15 uM, α-synuclein or polyglutamine proteins. |
| PC-45271 |
Pramiracetam
Cognitive activator
|
Pramiracetam (CI-879) is a central nervous system stimulant and nootropic agent and PREP (prolyl endopeptidase) inhibitor, shows cognition-restoring and neuroprotective properties. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-28805 |
L759-0762
RBM41 inhibitor
|
L759-0762 is a small molecule RNA-binding motif protein 41 (RBM41) inhibitor, disrupts the interaction between RBM41 and CKMT1B mRNA, selectively sensitizes TSCC cells to disulfidptosis under glucose deprivation by abolishing the protective function of RBM41. |
| PC-28754 |
CHI3L1 inhibitor DELC2
CHI3L1 inhibitor
|
DELC2 is a brain-penetrant Chitinase-3-like protein 1 (CHI3L1) inhibitor with MST KD of 10.31 uM, SPR KD of 8.7 uM, inhibits CHI3L1-RAGE association with IC50 of 2.25 uM in ELISA assays, suppresses RAGE-linked inflammatory signaling. |
| PC-28750 |
ZINC00784494
LCN2 inhibitor
|
ZINC00784494 is a small molecule inhibitor of Lipocalin-2 (LCN2), significantly decreases cell proliferation, cell viability and the AKT phosphorylation levels in ectopically expressing LCN2 MCF7 cells. |
| PC-28749 |
ZINC00640089
LCN2 inhibitor
|
ZINC00640089 is a small molecule inhibitor of Lipocalin-2 (LCN2), significantly decreases cell proliferation, cell viability and the AKT phosphorylation levels in ectopically expressing LCN2 MCF7 cells. |
