| Cat. No. |
Product Name |
Information |
| PC-27527 |
Rbin-2
Midasin inhibitor
|
Rbin-2 is a potent, reversible and selective inhibitor of AAA+ protein Midasin (Mdn1), inhibits eukaryotic ribosome biogenesis. |
| PC-27524 |
SAIT-PDZ-5179
GIPC1 inhibitor
|
SAIT-PDZ-5179 is a small molecule inhibitor of GAIP-interacting protein C terminus 1 (GIPC1), selectively target the PDZ domain of GIPC1 with ITC KD of 943 nM. |
| PC-27518 |
Zumododstat
DHODH inhibitor
|
Zumododstat is a potent, selective inhibitor of dihydro-orotate dehydrogenase (DHODH). |
| PC-27506 |
JXL020
MPC inhibitor
|
JXL020 is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 16.6 nM. |
| PC-27463 |
Alpha-D-Glucose-1-phosphate disodium
CAS 56401-20-8
|
α-D-Glucose-1-phosphate disodium (Fosdemannose) is a derivative of D-glucose as a starting material for glucuronic acid synthesis, also is a cytostatic compound, antibiotic and immunosuppressant. |
| PC-27438 |
Uniconazole
ABA catabolism inhibitor
|
Uniconazole is a plant growth retardant and potent inhibitor of abscisic acid (ABA) catabolism in Arabidopsis with IC50 of 68 nM for ABA 8’-hydroxylase, also is a potent competitive inhibitor of CYP707A3 activity with Ki of 8 nM, inhibits gibberellin biosynthesis. |
| PC-27435 |
DIBDO
GSDMD agonist
|
DIBDO is a small molecule gasdermin D (GSDMD) agonist, directly activates GSDMD bypassing Caspase-3, blocks Caspase-3 activation and induces GSDMD‐mediated pyroptosis in tumor cells. |
| PC-27433 |
Retro-2.2
Retrograde transport inhibitor
|
Retro-2.2 is a derivative of cellular retrograde transport inhibitor Retro-2, inhibits human respiratory syncytial virus (hRSV) replication in cell culture and impairs the ability of hRSV to form syncytia. |
| PC-27432 |
Retro-2 cycl
Retrograde transport inhibitor
|
Retro-2(cycl) (Retro-2 cycl) is a small molecule inhibitor of host retrograde trafficking, inhibits ricin and Shiga-like toxins (SLTs), inhibits infection by JCPyV, BKPyV, and simian virus 40 (SV40). |
| PC-27431 |
(S)-Retro-2.1
Retrograde transport inhibitor
|
Retro-2.1a ((S)-Retro-2.1) is a potent molecule to counteract the cytotoxic potential of ricin and Shiga toxin with EC50 of 23 nM and 54 nM, respectively, blocking retrograde transport and intracellular retrograde trafficking. |
| PC-27430 |
Retro-2.1
Retrograde transport inhibitor
|
Retro-2.1 is a small molecule inhibitor of retrograde transport, protects human cells against ricin and Stx by blocking retrograde toxin transport at the early endosomes-TGN interface, efficiently inhibits SARS-CoV-2 replication, inhibits JC polyomavirus (JCPyV) with EC50 of 3.9 uM. |
| PC-27423 |
Enterobactin
Iron chelator
|
Enterobactin is an iron transport compound and iron chelator from Salmonella typhimurium, not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages during the process of Salmonella typhimurium infecting macrophages, is also involved in the oxidative stress response of Escherichia coli. |
