| Cat. No. |
Product Name |
Information |
| PC-35205 |
IACS-010759
OXPHOS inhibitor
|
IACS-010759 (IACS010759) is a small molecule inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targets complex I of the mitochondrial electron transport chain. |
| PC-35175 |
VTI-1002
|
VTI-1002 is a first-in-class, highly potent, selective inhibitor of human Granzyme B (GzmB) with Ki of 4.4 nM, exhibits strong selectivity for GzmB over caspases 3-10, cathepsin G, and neutrophil elastase. |
| PC-35134 |
AA147
ATF6 agonist
|
AA147 is a specific, small molecule agonist of transcription factor ATF6, activates ATF6 and influences differentiation of stem cells. |
| PC-35108 |
BTZO-2
MIF activator
|
BTZO-2 is an active BTZO-1 derivative, an antioxidant response element-activator, provides protection against lethal endotoxic shock in mice.. |
| PC-35107 |
BTZO-1
MIF activator
|
BTZO-1 is a cardioprotective agent and Macrophage migration inhibitory factor (MIF) activator, binds to MIF with Kd of 68.6 nM, regulates ARE-mediated gene expression. |
| PC-35092 |
JI130
|
JI130 (JI-130) is a specific Hse1 inhibitor that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone, blocks Hes1-mediated transcriptional repression. |
| PC-35091 |
JI051
Hes1 inhibitor
|
JI051(JI-051) is a specific compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone, blocks Hes1-mediated transcriptional repression. |
| PC-63570 |
Siomycin A
FOXM1 inhibitor
|
Siomycin A (NSC 285116) is an antibiotic thiazole inhibitor of the oncogenic transcription factor FOXM1, down-regulates the transcriptional activity as well as the protein and mRNA abundance of FoxM1. |
| PC-63471 |
CD38 inhibitor 78c
CD38 inhibitor
|
CD38 inhibitor 78c is a potent, specific, reversible CD38 inhibitor with Ki of 14.5 nM for recombinant human CD38. |
| PC-63456 |
ERGi-USU
|
NSC139021 (NSC 139021, ERGi-USU) is a specific RIOK2 inhibitor, selectively inhibits ERG-positive cancer cell growth, directly binds (Kd=200 nM) and inhibits RIOK2 protein with IC50 of 220 nM (VCaP) and 360 nM (COLO320). |
| PC-63447 |
Syn-TEF1
|
Syn-TEF1 is a molecule actively enables transcription across repressive GAA repeats that silence frataxin expression in Friedreich's ataxia, license transcription elongation at targeted genomic loci. |
| PC-63409 |
JNJ-26993135
LTA4H inhibitor
|
JNJ-26993135 is a potent, selective leukotriene A4 hydrolase (LTA4H) inhibitor, inhibits both the epoxide hydrolase and aminopeptidase activities of recombinant human LTA4H with IC50 of 10 nM. |
