| Cat. No. |
Product Name |
Information |
| PC-73077 |
PCC0208017
pan-MARK inhibitor
|
PCC0208017 is a potent, selective dual small-molecule inhibitor of MARK3 and MARK4 with IC50 of 1.8 and 2.01 nM, respectively. |
| PC-73073 |
Perforin inhibitor 16
Perforin inhibitor
|
Perforin inhibitor 16 (Perforin-IN-16) is a small molecule Perforin inhibitor with IC50 of 1.13 uM in KHYG1 assay. |
| PC-73066 |
SCO-792
Enteropeptidase inhibitor
|
SCO-792 (SCO792) is a potent, selective, reversible enteropeptidase inhibitor with IC50 of 4.6 and 5.4 nM for rat and human enteropeptidase, respectively. |
| PC-73065 |
ASB17061
Chymase inhibitor
|
ASB17061 (ASB-17061) is an orally active, selective chymase inhibitor with IC50 of 0.03 uM and 0.02 uM for mMCP-4 and human chymase, respecitvely. |
| PC-73058 |
SWE101
sEH-P inhibitor
|
SWE101 (SWE-101, SWE 101) is a potent, selective, in vivo active inhibitor of soluble epoxide hydrolase (sEH) phosphatase domain (sEH-P) with IC50 of 58 nM. |
| PC-73057 |
AZ67
PFKFB3 inhibitor
|
AZ67 is a selective small molecule PFKFB3 inhibitor with IC50 of 18 nM, reduces cellular levels of F2,6BP with IC50 of 0.51 uM. |
| PC-73044 |
Ophiopogonin D
|
Ophiopogonin-D (OP-D) is one of steroidal saponins isolated from the root of the Chinese medicinal plant Ophiopogon japonicas, possesses anti-inflammatory and anti-oxidant properties. |
| PC-73029 |
EML417
PHF20 Tudor domain inhibitor
|
EML417 is a small molecule that selectively interactes with the Tudor domain of PHF20. |
| PC-73021 |
nTRD22
TDP-43-RNA inhibitor
|
nTRD22 is a small molecule that binds to the TDP-43 N-terminal domain (Kd=143 uM), causes allosteric modulation of the RNA binding domain (RRM) of TDP-43, resulting in decreased binding to RNA in vitro. |
| PC-73020 |
rTRD01
TDP-43-RNA inhibitor
|
rTRD01 is a specific small molecule that binds to TDP-43 RRM1 and RRM2 domains (Kd=89 uM), disrupts TDP-43 interaction with the hexanucleotide RNA repeat of the disease-linked c9orf 72 gene. |
| PC-73009 |
SPL-410
SPPL2a inhibitor
|
SPL-410 (SPL410) is a highly potent, selective, orally active inhibitor SPPL2a (Signal Peptide Peptidase Like 2a) with IC50 of 9 nM. |
| PC-73006 |
Pyrcoumin
dCTPP1 inhibitor
|
Pyrcoumin is a competitive inhibitor of dCTP pyrophosphatase 1 (dCTPP1, IC50=3.3 uM), inhibits Wnt signaling with IC50 of 8.4 uM in SuperTOPFlash reporter gene assays. |
